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Microbial Genomics Core

Overview of Services

As a collaborative laboratory (CoLab) incubator, our mission is to foster connections among interdisciplinary researchers who share a common interest in discovering the biomedical potential of the microbiome. The Microbial Genomics CoLab Incubator represents a new model for research and training at UCSF, offering collaborative data generation and analytical support for intramural and extramural investigators in parallel with embedded, experiential training opportunities in sequence-based microbiome profiling.

By providing collaborative expertise in next-generation sequencing, we facilitate the exploration of microbiome membership, gene content and transcriptional activity in relation to host outcomes and environmental exposures. We believe this approach in conjunction with complementary tools available within the Benoiff Center for Microbiome Medicine will lead to identification of actionable microbial targets and add a powerful new dimension to the diagnosis and treatment of medical conditions with unmet needs.

Our team has the expertise to offer assistance in the following areas:
- Project planning and management
- Sample collection, handling and storage recommendations
- Nucleic acid extraction
- Quantitative PCR
- Library preparation and sequencing
- Data interpretation
- Dissemination of findings

As a centralized facility, we are a cost-effective resource for basic, clinical and translational studies. We have developed streamlined workflows and optimized protocols for individual sample types. Our technology hub is located in the Medical Science Building. Infrastructure for microbiome analyses includes dedicated pre- and post-PCR spaces, Illumina NextSeq and MiSeq instruments, Oxford Nanopore MinION and access to HiSeq and NovaSeq platforms and HPC cluster.

We recognize that collaboration is bi-directional. Shadowing opportunities and workshops are available to investigators upon request. For assistance with grant proposals and manuscript preparation, please email Connie Ha, Director.

Leadership

Name Title Phone Email 
Connie W.Y. Ha, PhD Director 415-476-3777 connie.ha@ucsf.edu

Location and hours of operation

Hours Location
Monday-Friday 10am-5pm
513 Parnassus Avenue, S363

Links and Resources

  1. Microbial Genomics Core

Contacts

Name Role Phone Email Location
Connie W.Y. Ha, PhD
Director
 
415-476-3777
 
connie.ha@ucsf.edu
 

 
Kristin Dolan
Center Manager (Billing)
 

 
kristin.dolan@ucsf.edu
 

 
Preston Tasoff
Technician
 

 
preston.tasoff@ucsf.edu