BioSpecimen Processing Lab (BSPL)

Overview of Services

 
The BioSpecimen Processing Lab (BSPL) provides a suite of biospecimen services to support clinical, translational, and basic life sciences research: 
 
Biospecimen Acquisiton
Our team is specially trained in obtaining tissue and fluids in coordination with clinical procedures.  We work with the clinical teams to develop procedures that permit research specimen collection while not impacting clinical sample evaluation. 
  • Biopsy Collection - To ensure study requirements are communicated and high qualtity tissue is procured, a Research Associate attends biopsy procedures to receive tissue samples directly from the clinician and promptly preserve samples per study requirements.  
  • Surgical Collection - Our team of Pathologists' Assistants are trained to perform complex tissue dissection in accordance with pathology departmental guidelines while prioritizing patient diagnostic safety. Specimens are retreived from surgical suites, rapidly dissected and fresh, frozen and fixed tissue procured per study requirements.  
  • Available preparation methods:
    • Fresh tissue in media
    • Snap frozen, frozen in OCT, viable cryopreservation
      • Frozen tissue sectioning
    • Formalin-fixed tissue processed into FFPE blocks
      • Slide sectioning and staining

Biofluid Processing
Samples can be processed via one of our validated standard operating procedures, or according to specialized methods or sponsor requirements. 
  • Separation of blood components
  • PBMC isolation and preservation
  • Whole blood stimulations
  • DNA Extraction from blood, tissue and saliva
  • RNA extraction from PAXGene tubes

Biospecimen Custodianship
The UCSF Biobank provides secure, round-the-clock monitored biospecimen storage and inventory mangement via a regulatory-complient online database. 
  • Storage of blood, body fluids and tissue
  • Ambient, 4°C, -20°C -80°C, and liquid nitrogen sample storage
  • Controlled access, freezer alarms, back-up power and redundant temperature monitoring. 
  • 24/7 personnel coverage for off-hour freezer issues
  • Samples acquired and/or processed by the Biobank are 2D barcode labeled. 
  • Inventory management through MBioLIMS, a web-based regulatory compliant database to track samples through collection, processing, storage and distribution.

 

BSP Lab Guidelines for Liquid Sample Processing:

Hours of operation (all campuses):

  • Monday through Friday, 8am – 4:30pm. Last samples must be received by 4:00pm.
  • Samples with same-day shipments must be received by 1:30pm to meet outbound shipping cutoffs.
  • Samples with complex processing, such as PBMCs, whole blood stimulations, must be received by 2:30pm.

If same-day shipment samples are received past the cut-off time, samples will be shipped the next business day. Ambient samples are generally more time sensitive and require same-day shipment.

If your protocol has samples that will be collected past the same-day processing cut off time, please consult with your PI and/or sponsor for next steps. We can store samples overnight at ambient and refrigerated (4C) temperatures for processing the next day, but only with PI and/or sponsor approval

Scheduling sample drop-offs:

  • Schedule an appointment on our Outlook calendar by sending a calendar invite to biobank@ucsf.edu at least 24-hours in advance (last minute collections are subject to approval by on-site staff and are dependent on scheduled case volumes). Please include CC or study number, timepoint, and subject ID (SID) in the calendar invite title. Please attach the protocol/lab manual to the calendar invite. The duration of the calendar invite should be the expected times that the lab will receive samples.
  • Please notify us of sample delays or any changes to the calendar invite promptly via email/slack. Note: Samples should be dropped off promptly to the BSP labs following collection from the patient to ensure compliance with protocol requirements and to safeguard sample viability. Please do not drop off sample collections in batch if there are large delays between collections. Samples will no longer be picked up from clinical floors by the BSP team.
  • Label all blood tube samples and cryovials with SIDs prior to drop off.
    1. You are welcome to bring all shipping supplies and kits to the lab in advance. Please label all kits, shippers, and airway bills (AWBs) with the study or protocol number, SID, visit, and collection date.
  • Provide sponsor requisitions (if applicable) and complete all required fields prior to drop off: e.g. DOB, Patient ID, Site #, Visit date.

 

Management

Aras Mattis, MD PhD - Director (aras.mattis@ucsf.edu)

Kirsten Mowry, PA (ASCP)cm - BioSpecimen Processing Lab Manager (kirsten.mowry@ucsf.edu)

Ron Honrada - BioSpecimen Processing Lab Manager (ronald.honrada@ucsf.edu)

Zulma Finney - Lab Supervisor (zulma.finney@ucsf.edu)

 

Locations, Hours of operation, and Contacts

Mission Bay Campus:

Mission Bay Gateway-2 Lab

Hours Location

8:00am - 4:30 pm

Monday - Friday

(excluding UCSF campus holidays)        

1825 4th St. Room M2391 
San Francisco, CA 94158 

Lab Phone:  
(415) 502-6939  

Blood and Biopsy Pager:  
(415) 443-1501

Email: 
biobank@ucsf.edu

Mission Bay PCMB-5 Lab

Hours Location

8:00am - 6:00 pm

Monday - Friday

(excluding UCSF campus holidays)        

1825 4th St. Room L5144
San Francisco, CA 94158 

 Lab Phone:  
(415) 502-8516

Email: 
MZLab.CCRC@ucsf.edu

Mission Bay PCRC Lab

Hours Location

8:00am - 5:00 pm

Monday - Friday

(excluding UCSF campus holidays)        

1825 4th St. Room M6388 
San Francisco, CA 94158 

Lab Phone:  
(415) 502-9621 

Email: 
CCRCPedsLab@ucsf.edu

Parnassus Campus:

Parn-5 Lab

Hours Location

8:00am - 4:30 pm

Monday - Friday

(excluding UCSF campus holidays)        

513 Parnassus Ave. Room S526 
San Francisco, CA 94143 

Lab Phone:  
(415) 353-4263

Blood and Biopsy Pager:  
(415) 443-3670

Email: 
biobank@ucsf.edu

Parn-12 Lab

Hours Location

8:00am - 5:00 pm

Monday - Friday

(excluding UCSF campus holidays)        

513 Parnassus Ave. Room S1234 
San Francisco, CA 94143   

Lab Phone:  
(415) 476-2765

Email: 
GCRCLab@ucsf.edu

Mt. Zion Campus:

Mt. Zion Processing Lab and Freezer Farm

Hours Location

8:00am - 4:30 pm

Monday - Friday

(excluding UCSF campus holidays)        

2340 Sutter St. Room S241 
San Francisco, CA 94115  

Lab Phone:  
(415) 514-6945

Blood and Biopsy Pager:  
(415) 443-0495 

Email: 
biobank@ucsf.edu

Zuckerberg San Francisco General Hispital:

ZSFG Lab

Hours Location

8:00am - 4:30 pm

Monday - Friday

(excluding UCSF campus holidays)        

1001 Potrero Ave. Unit 5B  
San Francisco, CA 94110   

Lab Phone:  
(628) 206-3327

Email: 
SFGHLab.CCRC@ucsf.edu

San Francisco VA Hospital:

SFVA Lab

Hours Location

8:00am - 4:30 pm

Monday - Friday

(excluding UCSF campus holidays)        

4150 Clement Street MS 151CRO 
Building 203, Room 1A-14
San Francisco, CA 94121 

Email: 
VA.CRSReservations@ucsf.edu

Benioff Children's Hospital Oakland:

Oakland Lab

Hours Location

8:00am - 4:30 pm

Monday - Friday

(excluding UCSF campus holidays)        

 TBD

 

Pager Information

 

Surgical Tissue Collection

  • Kirsten Mowry, PA (ASCP)cm - (415) 443-1586
  • Reyna King, PA (ASCP)cm - (415) 443-1157
  • Kevin King, PA (ASCP)cm - (415) 443-0479

Biopsy Collection

  • Mt. Zion - (415) 443-0495
  • Parnassus (Parn-5) - (415) 443-3670
  • Mission Bay (Gateway-2) - (415) 443-1501

Links and Resources

  1. Team website: Biospecimen Processing Lab (BSPL)
  2. Team messaging: ucsfbiobank.slack.com
  3. UCSF Core Services and Equipment Search

Contacts

Name Role Phone Email Location
Kirsten Mowry, PA (ASCP)cm
Biospecimen Processing Lab Manager
 
415-443-1586 (pager)
 
kirsten.mowry@ucsf.edu
 
Parn-5 / Mt. Zion / MB Gateway-2
 
Reyna King, PA (ASCP)cm
Pathologists' Assistant - Tissue Acquisition
 
415-443-1157 (pager)
 
reyna.king@ucsf.edu
 
Parn-5 / Mt. Zion / MB Gateway-2
 
Sadeed Rashid
Sample Processing lead - Parnassus Blood, Biopsy and Biofluid Processing
 
415-353-4263
 
ahmad.rashid@ucsf.edu
 
Parn-5 Lab, Parn-12 Lab
 
Omid Jamdar
Biorepository Equipment Lead - Mt. Zion Blood, Biopsy and Biofluid Processing
 
415-514-6945
 
omid.jamdar@ucsf.edu
 
Mt Zion Lab and Freezer Farm
 
Raphael Lota
Mission Bay Blood, Biopsy and Biofluid Processing
 
415-502-6939
 
raphael.lota@ucsf.edu
 
MB Gateway-2
 
Alex Soepardi
Parnassus Blood and Biofluid Processing, Inventory
 
415-353-4263
 
alexander.soepardi@ucsf.edu
 
Parn-5
 
Ann Raja Somu
Parnassus Blood, Biopsy and Biofluid Processing
 
415-353-4263
 
ann.rajasomu@ucsf.edu
 
Parn-5
 
Kevin King, PA (ASCP)cm
Pathologists' Assistant - Tissue Acquisition
 
415-443-0479 (pager)
 
kevin.king2@ucsf.edu
 
Parn-5 / Mt. Zion / MB Gateway-2
 
Amber Derpinghaus
Mt. Zion Blood, Biopsy and Biofluid processing, Inventory
 
415-514-6945
 
aber.derpinghaus!ucsf.edu
 
Mt Zion Lab and Freezer Farm
 
Janet Zhen
Mt. Zion Inventory
 
415-514-6945
 
janet.zhen@ucsf.edu
 
Mt Zion Lab and Freezer Farm
 
Tin Truong
Mission Bay Blood, Biopsy and Biofluid Processing
 
415-502-6939
 
tin.truong@ucsf.edu
 
MB Gateway-2
 
Ron Honrada
ronald.honrada@ucsf.edu
 
415-218-3698
 
ronald.honrada@ucsf.edu
 
Parn-12, ZSFG, SFVA, BCH Oakland
 
Zulma Finney
zulma.finney@ucsf.edu
 
415-502-8516
 
zulma.finney@ucsf.edu
 
PCRC, PCMB-5
 
Brandon Baclay
Hildebrando.Baclay@ucsf.edu
 
415-502-8516
 
Hildebrando.Baclay@ucsf.edu
 
PCMB-5
 
Breiann Bolos
Breiann.Bolos@ucsf.edu
 
415-502-9621
 
Breiann.Bolos@ucsf.edu
 
PCRC
 
Genalyn Domingo
GenalynRose.Domingo@ucsf.edu
 
628-206-3327
 
GenalynRose.Domingo@ucsf.edu
 
ZSFG
 
Nikki Francisco
AnnaDominique.Francisco@ucsf.edu
 
415-502-8516
 
AnnaDominique.Francisco@ucsf.edu
 
PCMB-5
 
Vanessa Leung
Vanessa.Leung@ucsf.edu
 
415-476-2765
 
Vanessa.Leung@ucsf.edu
 
Parn-12
 
Derek See
Derek.See@ucsf.edu
 
415-476-2765
 
Derek.See@ucsf.edu
 
Parn-12
 
Vivian Tan
Vivian.Tan@ucsf.edu
 
415-502-8516
 
Vivian.Tan@ucsf.edu
 
PCMB-5
 
Douglas Wampler
Douglas.Wampler@ucsf.edu
 
628-206-3327
 
Douglas.Wampler@ucsf.edu
 
ZSFG
 

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