Biospecimen Services Program (BSP)

Overview of Services

 
The Biospecimen Services Program (BSP) provides a suite of biospecimen services to support clinical, translational, and basic life sciences research: 
 
Biospecimen Acquisiton
Our team is specially trained in obtaining tissue and fluids in coordination with clinical procedures.  We work with the clinical teams to develop procedures that permit research specimen collection while not impacting clinical sample evaluation. 
  • Biopsy Collection - To ensure study requirements are communicated and high qualtity tissue is procured, a Biobank Acquistion Technician attends biopsy procedures to preserve samples on-site, during biopsy procedure.  
  • Surgical Collection - Our team of Pathologists' Assistants are trained to perform complex tissue dissection in accordance with pathology departmental guidelines while prioritizing patient diagnostic safety. Specimens are retreived from surgical suites, rapidly dissected and fresh, frozen and fixed tissue procured.  

Biospecimen Processing
Samples can be processed via one of our validated standard operating procedures.  We can also process according your specialized methods or sponsor requirements. 
  • Separation of blood components
  • PBMC isolation and preservation
  • DNA Extraction from blood, tissue and saliva
  • RNA extraction from PAXGene tubes
  • Tissue dissection and preservation
  • Frozen tissue sectioning and slide preparation
  • Tissue processing to FFPE blocks
  • Viable cell/tissue preservation

Biospecimen Custodianship
The UCSF Biobank provides secure, round-the-clock monitored biospecimen storage and inventory mangement via a regulatory-complient online database. 
  • Storage of blood, body fluids and tissue
  • Ambient, 4°C, -20°C -80°C, and liquid nitrogen sample storage
  • Controlled access, freezer alarms, back-up power and redundant temperature monitoring. 
  • Samples acquired and/or processed by the Biobank are 2D barcode labeled. 
  • Currently utilizing REDCap, but transitioning the the MBioLIMS database system, a web-based regulatory compliant database to track samples through collection, processing, storage and distribution.

 

BSP Lab Guidelines for Liquid Sample Processing:

Hours of operation (all campuses):

  • Monday through Friday, 8am – 4:30pm. Last samples must be received by 4:00pm.
  • Samples with same-day shipments must be received by 1:30pm to meet outbound shipping cutoffs.
  • Samples with complex processing, such as PBMCs, whole blood stimulations, must be received by 2:30pm.

If same-day shipment samples are received past the cut-off time, samples will be shipped the next business day. Ambient samples are generally more time sensitive and require same-day shipment.

If your protocol has samples that will be collected past the same-day processing cut off time, please consult with your PI and/or sponsor for next steps. We can store samples overnight at ambient and refrigerated (4C) temperatures for processing the next day, but only with PI and/or sponsor approval

Scheduling sample drop-offs:

  • Schedule an appointment on our Outlook calendar by sending a calendar invite to biobank@ucsf.edu at least 24-hours in advance (last minute collections are subject to approval by on-site staff and are dependent on scheduled case volumes). Please include CC or study number, timepoint, and subject ID (SID) in the calendar invite title. Please attach the protocol/lab manual to the calendar invite. The duration of the calendar invite should be the expected times that the lab will receive samples.
  • Please notify us of sample delays or any changes to the calendar invite promptly via email/slack. Note: Samples should be dropped off promptly to the BSP labs following collection from the patient to ensure compliance with protocol requirements and to safeguard sample viability. Please do not drop off sample collections in batch if there are large delays between collections. Samples will no longer be picked up from clinical floors by the BSP team.
  • Label all blood tube samples and cryovials with SIDs prior to drop off.
    1. You are welcome to bring all shipping supplies and kits to the lab in advance. Please label all kits, shippers, and airway bills (AWBs) with the study or protocol number, SID, visit, and collection date.
  • Provide sponsor requisitions (if applicable) and complete all required fields prior to drop off: e.g. DOB, Patient ID, Site #, Visit date.

 

 

Management

Aras Mattis, MD PhD - Director (aras.mattis@ucsf.edu)

Kirsten Mowry, PA (ASCP)cm - Biospecimen Program Manager (kirsten.mowry@ucsf.edu)

 

Location and hours of operation

Hours Locations

8:00am - 4:30 pm

Monday - Friday

(excluding UCSF campus holidays)        

Mission Bay: 1825 4th St., M2391

Parnassus: 513 Parnassus Ave, S526

Mt. Zion:  2340 Sutter St., S241

Contact Information

Lab numbers:

  • Mt. Zion - (415) 514-3500
  • Parnassus - (415) 353-4263
  • Mission Bay - (415) 502-6939

Pager numbers:

Surgical Tissue Collection

  • Kirsten Mowry, PA (ASCP)cm - (415) 443-1586
  • Reyna King, PA (ASCP)cm - (415) 443-1157
  • Kevin King, PA (ASCP)cm - (415) 443-0479

Blood and Biopsy Collection

  • Mt. Zion - (415) 443-0495
  • Parnassus - (415) 443-3670
  • Mission Bay - (415) 443-1501

Links and Resources

  1. Team website: Biospecimen Resources Program
  2. Team email: biobank@ucsf.edu
  3. Team messaging: ucsfbiobank.slack.com
  4. UCSF Core Services and Equipment Search

Contacts

Name Role Phone Email Location
Kirsten Mowry, PA (ASCP)cm
Biospecimen Services Program Manager
 
415-443-1586 (pager)
 
kirsten.mowry@ucsf.edu
 
Parnassus / Mt. Zion / Mission Bay
 
Reyna King, PA (ASCP)cm
Pathologists' Assistant - Tissue Acquisition
 
415-443-1157 (pager)
 
reyna.king@ucsf.edu
 
Parnassus / Mt. Zion / Mission Bay
 
Sadeed Rashid
Sample Processing lead - Parnassus Blood, Biopsy and Biofluid Processing
 
415-353-4263
 
ahmad.rashid@ucsf.edu
 
513 Parnassus Ave, Room S-526
 
Omid Jamdar
Biorepository Equipment Lead - Mt. Zion Blood, Biopsy and Biofluid Processing
 
415-514-3500
 
omid.jamdar@ucsf.edu
 
2340 Sutter St, Room S-241
 
Raphael Lota
Mission Bay Blood, Biopsy and Biofluid Processing
 
415-502-6939
 
raphael.lota@ucsf.edu
 
1825 4th St, Room M-2391
 
Alex Soepardi
Parnassus Blood and Biofluid Processing, Inventory
 
415-353-4263
 
alexander.soepardi@ucsf.edu
 
513 Parnassus Ave, Room S-526
 
Ann Raja Somu
Parnassus Blood, Biopsy and Biofluid Processing
 
415-353-4263
 
ann.rajasomu@ucsf.edu
 
513 Parnassus Ave, Room S-526
 
Kevin King, PA (ASCP)cm
Pathologists' Assistant - Tissue Acquisition
 
415-443-0479 (pager)
 
kevin.king2@ucsf.edu
 
Parnassus / Mt. Zion / Mission Bay
 
Amber Derpinghaus
Mt. Zion Blood, Biopsy and Biofluid processing, Inventory
 
415-514-3500
 
aber.derpinghaus!ucsf.edu
 
2340 Sutter St, Room S-241
 
Janet Zhen
Mt. Zion Inventory
 
415-514-3500
 
janet.zhen@ucsf.edu
 
2340 Sutter St, Room S-241
 
Tin Truong
Mission Bay Blood, Biopsy and Biofluid Processing
 
415-502-6939
 
tin.truong@ucsf.edu
 
1825 4th St, Room M-2391
 

Service list


Search available services: View: by category alphabetically
Biopsy (1)
Services (6)
Surgical Collection (1)